Management of hepatitis B virus-related acute liver failure

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Management of hepatitis B virus-related acute liver failure.

Hepatitis B virus (HBV) is the most important cause of acute liver failure (ALF) in Eastern countries. HBV-related ALF may occur after acute HBV infection (A-ALF) or during acute exacerbation (flare) of chronic HBV infection (C-ALF). C-ALF may occur spontaneously or as a result of the effect of immunosuppression due to chemotherapeutic or immunosuppressive agents. The definition of HBV-related ...

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association of proton pump inhibitor therapy with hepatic encephalopathy in hepatitis b virus-related acute-on-chronic liver failure

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Serum from patients with hepatitis E virus-related acute liver failure induces human liver cell apoptosis

The pathogenesis of acute liver failure has not been fully elucidated. The present study investigated the effects of the serum from patients with hepatitis E virus (HEV)-related acute liver failure on human liver cell survival and apoptosis, and evaluated the protective effects of anti-lipopolysaccharide(LPS) antibody recognizing core polysaccharide against acute liver failure serum-induced apo...

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plasma interleukin-10: a likely predictive marker for hepatitis b virus-related acute-on-chronic liver failure

conclusions the assessment of plasma il-10 levels in chronic hepatitis b acute exacerbation may provide an early predictive marker for progression to hbv-aclf. results il-4, il-12p70 and ifn-γ were undetectable; il-1β, il-6, il-8, il-10 and tnf-α levels were significantly higher than in nc. moreover, cytokines reached the highest levels in acute exacerbation of chb, with the exception of il-2 a...

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Hepatitis B virus genotype and basal core promoter/precore mutations are associated with hepatitis B-related acute-on-chronic liver failure without pre-existing liver cirrhosis

The study was undertaken to investigate the features and clinical implications of hepatitis B virus (HBV) genotypes, basal core promoter (BCP) and precore (PC) mutations in hepatitis B-related acute-on-chronic liver failure (HB-ACLF). Samples from 75 patients with HB-ACLF and without pre-existing liver cirrhosis and 328 age-matched patients with chronic hepatitis B (CHB) were analyzed. HBV geno...

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ژورنال

عنوان ژورنال: Clinical Journal of Gastroenterology

سال: 2014

ISSN: 1865-7257,1865-7265

DOI: 10.1007/s12328-013-0447-1